Nissl bodies, also called nissl substance, are granules in the cytoplasm of nerve cell bodies that are strongly stained by basic dyes and appear as basophilic clumps on light microscopy. They consist of aggregates of free polyribosomes and rough endoplasmic reticulum. These granules are scattered throughout the cytoplasm of nerve cell bodies and may extend into the proximal parts of large dendrites.
Nissl bodies are involved in protein synthetic activity and are more prominent in large active nerve cells that such spinal motor neurons.
English: Nissl bodies
Latin: Substantia chromatophilica
Learn about the various features of neurons in the following study unit:
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