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Nissl bodies

Recommended video: Neurons [11:24]
Neurons are the basic building blocks of the nervous system.

Nissl bodies, also called nissl substance, are granules in the cytoplasm of nerve cell bodies that are strongly stained by basic dyes and appear as basophilic clumps on light microscopy. They consist of aggregates of free polyribosomes and rough endoplasmic reticulum. These granules are scattered throughout the cytoplasm of nerve cell bodies and may extend into the proximal parts of large dendrites.

Nissl bodies are involved in protein synthetic activity and are more prominent in large active nerve cells that such spinal motor neurons.

Terminology English: Nissl bodies
Substantia chromatophilica
Function Protein synthesis

Learn about the various features of neurons in the following study unit:

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