Connection lost. Please refresh the page.
Get help How to study Login Register
Ready to learn?
Pick your favorite study tool

Cerebral peduncle

The cerebral peduncle refers to the entire region of the midbrain (mesencephalon) located ventral (anterior) to the tectum, the part of the midbrain dorasl (posterior) to the cerebral aqueduct. It comprises the crus cerebri, tegmentum and the substantia nigra.

The crus cerebri is the most prominent part of the cerebral peduncle. It refers to the massive bundle of fibers located on the anterolateral aspects of the peduncle. These fibers are predominantly corticospinal tracts that carry somatic motor signals from the primary motor cortex down to the spinal cord, facilitating voluntary motor movements. The crus cerebri also carries corticonuclear (corticobulbar) fibers, which are responsible for motor control of the face and neck via the cranial nerves. Additionally, it contains corticopontine fibres which descend from the cerebral cortex to pontine nuclei.

The tegmentum, on the other hand, contains important nuclei and tracts including the red nucleusperiaqueductal grey matter and the reticular formation, which play roles in motor coordination, pain processing and arousal, respectively.

The substantia nigra, which is a large nucleus located posterior to the crus cerebri, is important for movement control. Its degeneration is a hallmark of Parkinson's disease.

The basis pedunculi, another term associated with this region, is used to describe the combined structure of the crus cerebri and the substantia nigra. In common usage, the terms crus cerebri, cerebral peduncle and basis pedunculi are often used interchangeably to refer to the large fiber bundle in the front part of the peduncle.

Terminology English: Cerebral peduncle

 Pedunculus cerebri
Synonym: Pedunculus cerebralis
Definition Region of the midbrain below the tectum
Function Motor control, movement control and coordination
Sensory information relay, pain processing, arousal and alertness

Learn more about the cerebral peduncle in the following study unit:

Cerebral peduncle: want to learn more about it?

Our engaging videos, interactive quizzes, in-depth articles and HD atlas are here to get you top results faster.

What do you prefer to learn with?

“I would honestly say that Kenhub cut my study time in half.” – Read more.

Kim Bengochea Kim Bengochea, Regis University, Denver
© Unless stated otherwise, all content, including illustrations are exclusive property of Kenhub GmbH, and are protected by German and international copyright laws. All rights reserved.

Register now and grab your free ultimate anatomy study guide!