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Blood supply of the Heart


The coronary circulation is responsible for nourishing the heart during its tireless effort in pumping blood around the body. This article will highlight the main anatomical points of this arterial and venous systems as well as a common pathological coronary disorder.

Recommended video: Coronary arteries and cardiac veins
Overview of the main coronary arteries and cardiac veins.


Left coronary artery - anterior view

The first branches that radiate from the ascending aorta, as it emerges from the left ventricle, are the left and right coronary arteries, which directly provide an arterial blood supply to the cardiac muscle. They arise from the bilateral aortic sinuses which are situated just distal to the aortic valve.

The left coronary artery runs between the left atrium and the trunk of the pulmonary artery. It supplies the left atrium, a large portion of the left ventricle, a small portion of the right ventricle, the interventricular septum and the sinoatrial node in approximately forty percent of the population. Its two main branches consist of the circumflex branch that supplies the posterior surface of the heart by running on its left side within the atrioventricular groove, as well as an anterior interventricular branch which runs inferiorly down the interventricular groove to the cardiac apex where it anastomoses with the posterior interventricular artery.

The right coronary artery passes through the atrioventricular groove to the right side and continues on to the posterior surface of the heart. It supplies the right atrium, the majority of the right ventricle, the portion of the left ventricle that communicates with the diaphragm, areas of the interatrial and interventricular septum, the sinoatrial node in around sixty percent of the population and the atrioventricular node in general. This artery further divides into several branches including the sinoatrial nodal branch, the right marginal branch, which runs to the right margin of the heart, and the atrioventricular nodal branch, which supplies the atrioventricular node at the junction of the four heart chambers within the septae on the posterior side of the heart. Lastly, a posterior interventricular branch runs along the posterior interventricular groove.

Coronary sinus - posterior view

The venous drainage of the heart is primarily governed by the coronary sinus, with the secondary help of the anterior cardiac veins which enter the right atrium directly and the smallest cardiac veins that open directly into the heart chambers. The coronary sinus runs transversely along the posterior surface of the heart in the coronary groove and is a particularly wide vein as it receives blood from the great cardiac vein, the middle cardiac vein, the small cardiac veins, the left marginal vein and the left posterior ventricular veins. The great cardiac veins run superiorly in the anterior interventricular groove and enters the coronary sinus on the left side. The middle cardiac vein, which is also known as the posterior interventricular vein, follows suit but in the posterior interventricular groove, entering the coronary sinus on the opposing side.


Coronary artery disease is one of the many terms, including ischaemic heart disease or atherosclerotic heart disease, that is used to describe the narrowing of the inner walls of the arteries that supply the heart. This condition is very serious and may prove fatal since it is the most common type of heart disease and the most frequent cause of heart attack. The most obvious symptom of coronary artery stenosis is angina, or chest pain in the region of the heart which is situated behind the left breast bone. Risk factors for acquiring this condition include hypertension, hypercholesterolemia, smoking, hyperglycemia, hemostatic factors, genetics, high levels of lipoprotein, lack of exercise, alcohol consumption, stress, low levels of dietary antioxidants, obesity, low hemoglobin levels and old age. A positive diagnosis is obtained via various cardiac examinations including an exercise ECG, electrocardiography or an ultrasound to name but a few. Preventative measures include a balanced diet with plenty of exercise. Treatment for those already suffering from this ailment include various medications and sometimes surgical intervention.

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Show references


  • Frank H. Netter, MD, Atlas of Human Anatomy, Fifth Edition, Saunders - Elsevier, Chapter 3 Thorax, Subchapter 22 Heart, Guide Thorax: Heart Page 113 to 114.


  • Dr. Alexandra Sieroslawska


  • Left coronary artery - anterior view - Yousun Koh 
  • Coronary sinus - posterior view - Yousun Koh 
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