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Great saphenous vein

Recommended video: Main veins of the lower limb [11:22]
Main veins and tributaries of the lower extremity.
Great saphenous vein (Vena saphena magna)

The great saphenous vein is the largest vein of the human body. It is also known as the long saphenous vein. The great saphenous vein starts from the medial marginal vein of foot, runs superficially along the length of the lower limb, to finally empty into the femoral vein.

Just like the other veins of the lower limb, the great saphenous vein is capable of returning blood back to the heart against gravity. There is a special pumping mechanism and the presence of valves that ensure venous return. The venous system of the body is divided into a superficial and deep system. The superficial system is visible on the surface of our skin, if a tourniquet is applied. These veins are commonly used to sample blood for blood tests. The superficial veins drain into deep veins (which share the same names as the arteries they run along). These deep veins return blood to the inferior and superior vena cava, and then to the right atrium of the heart.

In this article, we will discuss the anatomy and clinical relevance of the great saphenous vein.

Key facts about the great saphenous vein
Origin Medial marginal vein of foot
Tributaries Small saphenous, accessory saphenous, anterior femoral cutaneous, superficial epigastric, superficial circumflex iliac, superficial external pudendal veins
Drains to Femoral vein
  1. Anatomy
    1. Location
    2. Course
    3. Femoral triangle
  2. Summary
  3. Clinical points
  4. Sources
+ Show all



The great saphenous vein is a large superficial vein of the lower limb. It drains into the femoral vein, which is the medial most structure in the femoral triangle. The lateral border of the femoral triangle is formed by the medial border of sartorius, the medial border of the femoral triangle is formed by the medial border of adductor longus and the inguinal ligament forms the base of the triangle. The point at which it drains into the femoral vein is known as the saphenofemoral junction.


The great saphenous vein originates from the dorsal vein of the hallux, which merges with the dorsal venous arch of the foot. The vein then runs anterior to the medial malleolus (a relatively easy area to locate the vein). The vein ascends up the medial surface of the leg, and then runs posterior to the medial epicondyle of the femur. It then runs upward in the thigh and passes over the medial surface of the thigh. In the thigh it is accompanied by branches of the medial femoral cutaneous nerves , and at the knee, in the leg and the foot the vein is closely related to the saphenous artery (a branch of the descending genicular artery). The great saphenous vein then passes through an opening in the fascia lata i.e. the saphenous opening. It continues as an arch to join the femoral vein within the medial region of the femoral triangle.

Explore our study unit to learn everything about the veins of the lower extremity.

Femoral triangle

The great saphenous vein is the medial most structure in the femoral triangle. Lateral to it, is a space that allows for expansion of the vein during increases venous return. Situated on the lateral side of the great saphenous vein is the femoral artery. The most lateral structure is the femoral nerve (posterior divisions of the anterior rami of spinal nerves L2-L4), which runs close to the anterior superior iliac spine, and runs beneath the inguinal ligament. There are numerous valves in this vein, that ensure blood flows in the correct direction.

There is a valve covering the saphenofemoral junction (where the saphenous vein joins the femoral vein), and separates the superficial and deep venous system.

The great saphenous vein receives smaller veins from the ankle and foot. These include the medial marginal vein (drains the sole of the foot), the small saphenous vein (it has numerous connections with its smaller counterpart in the lower region of the leg). In leg it is connected to short saphenous vein and with deep veins through perforating veins. Close to knee it receives three large tributaries, in thigh it receives many tributaries that are posteromedial i.e accessory saphenous vein, anterolateral i.e anterior femoral cutaneous vein and peri-inguinal which are superficial epigastric, superficial circumflex iliac and superficial external pudendal veins. It also receives connecting branches from the popliteal vein via another perforator. As the vein ascends in the thigh it receives branches from the common femoral vein.

This quiz challenges you on the main veins of the lower limb.

Veins can be very tricky to identify. Why not start practicing now by making your own structure identification flashcards? 


  • The great saphenous vein is a superficial vein of the lower limb
  • It drains the superficial structures of the medial thigh and leg
  • It drains into the common femoral vein at the saphenofemoral junction
  • It receives blood from the small saphenous vein, medial marginal vein of the ankle, as well as named perforators from the veins of the thigh and knee region
  • It is harvested for use in CABG procedures
  • The popliteal vein connects to the great saphenous vein via a perforating vein (of Boyd)
  • Another perforating vein (of Dodd) connects the common femoral vein to the great saphenous vein

Ready to round up the story about the veins of the lower limb? Check out our special, customizable, quiz!

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