Female reproductive organs
The female sex organs consist of both internal and external genitalia. Together they comprise the female reproductive system, supporting sexual and reproductive activities. The external genital organs, or vulva, are held by the female perineum. These are the mons pubis, labia majora and minora, clitoris, vestibule, vestibular bulb and glands. The vagina, uterus, ovaries and uterine tubes compose the internal genital organs.
Female reproductive organs undergo substantial structural and functional changes every month. These changes are not only there to make women’s lives miserable, they also have a crucial function in the initiation of pregnancy. If pregnancy does not occur, the proliferated endometrial lining breaks down and sheds, passing through the vagina as menstrual blood. These activities occur under the influence of hormones secreted by female sex organs (ovaries), as determined by the endocrine system. The female sex hormones also have a major role in sexual maturation.
|Internal genitalia||Vagina, uterus, ovaries, uterine tubes|
|External genitalia||Mons pubis, labia majora, labia minora, clitoris, vestibule, vestibular bulb, vestibular glands|
Internal genitalia: uterine artery, ovarian artery, vaginal artery, internal iliac artery
External genitalia: internal pudendal artery, external pudendal artery
Internal genitalia: thoracolumbar nerves, lesser splanchnic nerves, hypogastric nerve (sympathetic), pelvic splanchnic nerves, vagus nerve (parasympathetic)
External genitalia: ilioinguinal nerve, genitofemoral nerve, pudendal nerve, posterior cutaneous nerve of the thigh (sensory), uterovaginal nerve plexus (parasympathetic)
Internal genitalia: para-aortic, iliac (internal and external), superficial inguinal, lumbar, and sacral lymph nodes
External genitalia: superficial and deep inguinal lymph nodes, internal iliac lymph nodes
|Clinical points||True hermaphroditism, Pseudohermaphroditism|
This article describes the complex, yet fascinating female reproductive anatomy, its blood supply and innervation.
- Internal genitalia
- External genitalia
- Menstrual cycle
- Video tutorials
- Clinical relations
- Related diagrams and images
Internal genitalia are the female reproductive organs that are located inside the pelvic cavity. They include the following:
The vagina is the outermost internal female sex organ. It extends from the uterus to the vulva (external genitalia). Functionally, it facilitates menstruation, sexual intercourse and childbirth. The vagina is located posterior to the urinary bladder and urethra, and anterior to the rectum.
The upper end of the vagina is attached to the cervix of the uterus. These structures form a pouch (vaginal fornix) which has anterior, posterior, and lateral parts. The lower end of the vagina (vaginal orifice) opens into the vaginal vestibule just behind the urethral orifice. The vaginal orifice may be partially covered with a membrane called hymen.
The vagina is supplied by branches of the internal iliac artery; uterine, vaginal and internal pudendal arteries. Venous drainage of the vagina is provided by the vaginal veins which flow into the internal iliac veins. Nervous supply is derived from the:
- Inferior hypogastric plexus via the uterovaginal plexus - the sympathetic and parasympathetic fibers are conveyed by the thoracolumbar (T12-L1) and pelvic splanchnic nerves (S2-S4), respectively.
- Pudendal nerve via the deep perineal nerve.
Lymph is drained from the vagina into the iliac and superficial inguinal lymph nodes.
For more details about the vagina, its anatomy, blood supply and innervation, check out the following article and video:
The uterus (womb) is a hollow muscular organ located deep within the pelvic cavity. Anterior to the rectum and posterosuperiorly to the urinary bladder, the uterus normally sits in a position of anteversion and anteflexion. The endometrial lining of the uterus proliferates each month in preparation for embryo implantation. If fertilization occurs, the uterus acts to house the growing fetus and its placenta. If pregnancy does not occur, the endometrial lining is shed during menstruation.
The uterus is divided into three parts:
- Body (corpus) - the main part of the uterus, connected to the uterine (fallopian) tubes via the uterine horns. The body has a base (fundus) and an internal chamber (uterine cavity).
- Isthmus - the constricted part of the uterus, located between the body and the cervix.
- Cervix - the inferior portion of the uterus. It consists of two parts (supravaginal, vaginal), two openings (internal os, external os) and a cervical canal.
The uterus is partially covered by peritoneum. As it reflects from the uterus to the rectum and urinary bladder, two folds are formed: the rectouterine pouch (of Douglas) and the vesicouterine pouch, respectively. Several peritoneal ligaments support the uterus and hold it in place: broad ligament, round ligament, cardinal ligament, uterosacral ligament and pubocervical ligament.
Check how well you've understood! Our labeled diagrams and quizzes on the female reproductive system are the best place to start.
The uterus is supplied mainly by the uterine artery which arises from the internal iliac artery. The superior branch of the uterine artery supplies the body and fundus, while the inferior branch supplies the cervix. The venous blood of the uterus is drained via the uterine venous plexus into the internal iliac vein.
The uterus receives innervation from the inferior hypogastric plexus via the uterovaginal nervous plexus, similar to the vagina. Lymphatic drainage of the uterus is into the lumbar, superficial inguinal, iliac (internal, external) and sacral lymph nodes.
To wrap your head around these seemingly complicated structures and their relations, take a better look at the uterus, its ligaments and related structures with the following video tutorials and articles:
The ovaries are bilateral female gonads and the equivalent of the male testes. They release the ovum (egg) for the purpose of fertilization. In addition, they act as endocrine glands, secreting various hormones necessary for fertility, menstruation and sexual maturation of the female.
Each ovary is located in the ovarian fossa of the true pelvis, adjacent to the uterus and below the fallopian tubes. The ovary contains four surfaces (anterior, posterior, medial, lateral) and two poles (superior, inferior). It is held in its normal position by several paired ligaments: suspensory ligament of the ovary, proper ovarian ligaments (ligament of ovary) and mesovarium.
Ovaries receive arterial supply from the ovarian arteries, which arise from the abdominal aorta. These blood vessels reach the gonads by traveling within the suspensory ligaments.
Venous blood of the ovaries is drained by the pampiniform plexus. These veins later coalesce and form the ovarian veins. The right ovarian vein drains into the inferior vena cava, whereas the left ovarian vein flows into the left renal vein.
The ovaries are innervated by the ovarian nervous plexus which receives fibers from the aortic, renal and hypogastric (superior, inferior) plexuses. Sympathetic fibers are derived from the lesser splanchnic nerves (T10-T11). Parasympathetic innervation arises from the pelvic splanchnic nerves (S2-S4). Lumbar lymph nodes are responsible for lymphatic drainage of the ovaries.
To find out more about the anatomy and neurovasculature of the ovary, watch the following videos and read these articles:
The uterine (fallopian) tubes are bilateral muscular organs that extend from the uterine horns to the superior poles of the ovaries. The fallopian tubes represent the usual site for ovum fertilization. They also transport the resulting zygote into the uterus for implantation.
The uterine tubes are intraperitoneal organs, covered completely by a part of the broad ligament of the uterus called the mesosalpinx. They consist of four main parts:
- Infundibulum - the distal part of the uterine tube that opens into the peritoneal cavity via the abdominal ostium. The infundibulum contains finger-like projections called fimbriae which extend over the medial surface of the ovaries.
- Ampulla - is the longest and widest part of the uterine tube. It is the most common site of fertilization.
- Isthmus - is the narrowest part of the uterine tube
- Intramural (uterine) part - it communicates directly with the uterine cavity via the uterine ostium.
The uterine tube receives arterial supply from the uterine and ovarian arteries. The former is a branch of the internal iliac artery, and the latter arises from the abdominal aorta. Venous drainage of the uterine tubes is mediated by the tubal veins. These drain into the uterine and pampiniform venous plexuses.
The uterine tube receives sympathetic innervation from the superior hypogastric plexus (T10-L2) via the hypogastric nerve. Parasympathetic innervation stems from the pelvic splanchnic nerves and the vagus nerve. Lymph is drained from the uterine tubes to the para-aortic, internal iliac and inguinal nodes.
For more details about the uterine tubes, their embryology, histology, blood supply and innervation, check out the following article!
The external genitalia (vulva) are the organs of the female reproductive system located in the perineum, outside the pelvis. They include the following:
- Mons pubis
- Labia majora
- Labia minora
- Vestibular bulb
- Vestibular glands
The mons pubis is a mass of subcutaneous adipose tissue located anterior to the pubic symphysis. The skin overlying the mons pubis is covered with a triangular patch of pubic hair.
Labia majora are two longitudinal skin folds covered with pubic hair. They are the most lateral part of the vulva, extending from the mons pubis to the perineum. The cleft between the labia majora is called the pudendal cleft. It contains the labia minora and the vestibule. The two labia majora merge anteriorly (anterior commissure) and posteriorly (posterior commissure). The labia majora are homologous to the scrotum of the male.
Labia minora are two longitudinal, thin and hairless skin folds found between the labia majora. They surround the vaginal vestibule and its urethral and vaginal orifices. The labia minora contribute to the formation of the prepuce and frenulum of the clitoris.
The clitoris is an erectile organ responsible for sexual sensations. It is analogous to the male penis. Located at the most superior part of the vulvar vestibule, the clitoris is surrounded by the anterior part of the labia minora. It has three parts: root, body and glans. The body consists of two corpora cavernosa and two attachment points (crura).
The region between the labia minora is called the vestibule. This perineal area contains the vaginal orifice, opening of the female urethra and the openings for the excretory ducts of the greater and lesser vestibular glands.
There are three types of glands that open into the vestibule:
- The greater vestibular (Bartholin's) glands are found on each side of the vestibule. They are homologous to the bulbourethral glands in the male and serve to lubricate the vulva during sexual intercourse
- The lesser vestibular glands are located between the urethral and vaginal orifices. These glands are homologous to the male prostate.
The bulbs of vestibule are a pair of subcutaneous erectile tissues analogous to the penile bulb and corpus spongiosum in males. They extend on each side of the vestibule and join in front of the urethral orifices.
Blood supply and innervation
The external genitalia are supplied by the pudendal arteries (internal, external) which are branches of the internal iliac and femoral arteries, respectively. Venous drainage is mediated by the internal and external pudendal veins.
The anterior aspect of the vulva receives sensory innervation from the ilioinguinal nerve and genitofemoral nerve. The posterior aspect is supplied by the pudendal nerve and the posterior cutaneous nerve of the thigh. The bulb of the vestibule and the clitoris receive parasympathetic innervation from the uterovaginal nerve plexus.
Lymph from the external genitalia is drained by the superficial and deep inguinal lymph nodes, or directly into the internal iliac lymph nodes.
Want to know more about the female external genitalia? Check out the articles below including a clinical case about female genital mutilation!
The menstrual cycle is a series of hormonally-induced monthly changes to the female reproductive organs. It involves two cycles that interact and overlap; the ovarian cycle and the uterine cycle. The ovarian cycle goes through three phases; follicular, ovulation and luteal. Together these allow for the maturation and release of the ovum.
Do you want to revise effectively, save time and improve long-term retention? Kenhub's anatomy quiz questions are your secret to success because they are diverse, fully portable and incorporate spaced repetition!
The uterine cycle also has three phases; menses, proliferative and secretory. The uterine phases act to prepare the uterus for potential fertilization and impending pregnancy.
- Follicular phase - (Days 1-14) The ovarian follicles mature and prepare for ovulation. This phase overlaps with the proliferative phase of the uterine cycle which prepares the lining of the uterus for implantation.
- Ovulation - (Typically day 14) The ovarian follicle ruptures and releases an ovum.
- Luteal Phase - (Days 14 - 28) The ovarian follicle is transformed into a hormone secreting corpus luteum. This phase corresponds to the secretory phase of the uterine cycle in which the endometrium becomes a nutritionally rich environment for the implantation of the fertilized egg.
- Menstruation - If no ovum is fertilized, the endometrial lining is shed, which signifies the beginning of menses, the first phase of the uterine cycle. If an ovum is fertilized the pregnancy will be maintained by a series of hormonal cascades.
To find out more details about the menstrual cycle, check out the following articles. After that, you can read the article about menorrhagia to see what happens if something in this process goes wrong.
Hermaphroditism is a disorder of sexual differentiation characterized by the existence of both female and male genitalia in one individual. True hermaphroditism is the condition in which an individual contains both female and male reproductive organs, either by having both the ovary and the testis separately, or combined in the form of ovotestis. At birth, these individuals are typically regarded as males. However, in puberty they develop breasts and start menstruating.
Pseudohermaphroditism is a condition characterized by a discrepancy between the internal and external genitalia. In female pseudohermaphroditism, the individual contains a female chromosomal constitution (46, XX), female internal genitalia, and male external genitalia. In male pseudohermaphroditism, the individual contains a male chromosomal constitution (46, XY) male internal genitalia, and female or ambiguous external genitalia.